Sodium/potassium proportion alter are in the blood circulation pressure alter: possibility of society method for salt/potassium proportion loss of health checkup

Sodium/potassium proportion alter are in the blood circulation pressure alter: possibility of society method for salt/potassium proportion loss of health checkup

Recently, the sodium (Na)/potassium (K) ratio was reported to be associated with blood pressure (BP). A Na/K ratio self-monitoring device using spot urine was established recently. Here, we assessed whether the urinary Na/K ratio change measured using the Na/K device was associated with BP change in a health checkup setting. We targeted 12,890 participants who attended the health checkup in Tome City, Miyagi between 2017 and 2018. Tome City introduced urinary Na/K ratio measurements during health checkups since 2017. For each year, we compared the baseline characteristics according to the urinary Na/K ratio and BP level. We assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, and change in body mass index (BMI) and alcohol intake. The average urinary Na/K ratio was significantly lower in 2018 than in 2017 (5.4 ± 3.0 to 4.9 ± 2.2, P < 0.01). The systolic BP of the participants in 2018 (130.9 ± 17.4 mmHg) was lower than that in 2017 (132.1 ± 17.9 mmHg). Moreover, the change in systolic BP and diastolic BP was positively associated with the change in urinary Na/K ratio. In conclusion, the association of the change in urinary Na/K ratio with hypertension and changes in systolic and diastolic BP can be explained by a change in alcohol intake, BMI, and urinary Na/K ratio. Therefore, measuring the urinary Na/K ratio in community settings is a potential population approach for counteracting hypertension.

Introduction

Recently, it absolutely was stated that this new sodium (Na)/potassium (K) ratio is actually for the blood pressure (BP) into the a corner-sectional analysis [step one,dos,step three,4]. This might be expected given that highest Na and you will K intake are recognized is pertaining to higher and you may low BP, correspondingly [5,six,7]. Additionally, research has already been presented on the reference thinking and you can items contributing to the latest Na/K proportion in the past seasons [8, 9].

Sodium/potassium ratio alter is regarding the blood pressure levels changes: chances of people approach for sodium/potassium proportion lack of health checkup

When you look at the a residential district setting, it is hard for us to assess the real Na consumption as Na intake are traditionally analyzed from the 24-h urine range. In the event several equations to own estimating Na intake or K intake using everyday destination pee have been has just depending, this type of equations are not exact sufficient to render feedback on the anyone [ten,11,12]. In addition, since equation needs calculating Na, K, and you may creatinine accounts in the a research, it takes several weeks to obtain the outcomes for some one. Even in the event people are aware that sodium protection is good for minimizing BP, he’s got no chance off determining its Na level.

Has just, an excellent Na/K proportion care about-overseeing device using spot urine is actually based . Although it don’t assess the genuine Na consumption level, it will offer viewpoints regarding the urinary Na/K balance within seconds. Additionally, an enthusiastic interventional otherwise observational study with this display screen advised that is a good unit so you can imagine brand new urinary Na/K proportion [thirteen, 14].

Therefore, although we have no way to measure the Na/K proportion inside the fitness checkup options, we thought that determining the newest urinary Na/K ratio for the a health checkup web site could have the potential to include feedback with the standard population about their Na/K proportion and will have an effect on feeling change, change in action, Na/K ratio cures, and you can BP cures. In this investigation, we assessed whether the urinary Na/K proportion change mentioned on Na/K ratio dimension equipment was in the BP changes independent out-of confounding items instance body mass index (BMI) change and alter during the alcohol intake and you can opposed farmersonly sorun the newest BP peak and you may urinary Na/K proportion from the community top.